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Nature considered that emails had not shown anything that undermined the scientific case on human caused global warming, or raised any substantive reasons for concern about the researchers' own papers.Independent reviews by Fact Check and the Associated Press said that the emails did not affect evidence that man-made global warming is a real threat, and said that emails were being misrepresented to support unfounded claims of scientific misconduct.

In response, the president's science adviser John Holdren said that the science was proper, and the emails only concerned a fraction of the research.In addition, the investigation would review CRU's compliance with Freedom of Information Act requests and also "make recommendations about the management, governance and security structures for CRU and the security, integrity and release of the data it holds." On 22 March 2010 the university announced the composition of an independent Science Assessment Panel to reassess key CRU papers which have already been peer reviewed and published in journals.The panel did not seek to evaluate the science itself, but rather whether "the conclusions [reached by the CRU] represented an honest and scientifically justified interpretation of the data." The university consulted with the Royal Society in establishing the panel.He is a valued and important scientist." The university announced it would conduct an independent review into issues including Freedom of Information requests to the Climatic Research Unit: it would "address the issue of data security, an assessment of how we responded to a deluge of Freedom of Information requests, and any other relevant issues which the independent reviewer advises should be addressed." Two days later, the university announced that Sir Muir Russell would chair the inquiry, which would be known as the Independent Climate Change Email Review, and would "examine email exchanges to determine whether there is evidence of suppression or manipulation of data".The review would also scrutinise the CRU's policies and practices for "acquiring, assembling, subjecting to peer review, and disseminating data and research findings" and "their compliance or otherwise with best scientific practice".

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